The goal of our research is to understand RNA regulatory networks and their dysregulation in human disease.
One focus area of the lab is determining how RNA regulation controls the timing of stimulus responses, specifically focusing on adrenal steroid hormone production in human and mouse models.
Another main focus is determining how dyregulation of mRNA translation mechanisms drives a variety of cancers (multiple myeloma, head and neck cancers, and breast cancer) and how we can target these mechanisms specifically.
The research in the lab relies on generating and analyzing transcriptome-wide datasets. As such, computational biology approaches are a major part of every project.
The lab is in the Department of Biochemistry and Molecular Genetics.
We are members of the vibrant and interactive RNA Bioscience Initiative.
Temporal coordination of post-transcriptional stimulus responses
AngII-stimulated aldosterone production
Human adrenal
differerntiation
and
pathophysiology
In vivo models of ovarian and adrenal steroidogenesis
Translatomics:
targeting mRNA translation
in cancer
and
beta cell autoimmunity
Where we work
CONTACT
Contact Neel directly:
neelanjan'dot'mukherjee'at'cuanschutz'dot'edu
Lab
Location: RC1S 10403A
Phone: 303-724-3567
Office
Location: RC1S 10115
Phone: 303-724-1623
Shipping address:
University of Colorado School of Medicine
Research Complex 1 South L18-10403A
12801 E 17th Ave, Aurora, CO 80045